Abstract: The maximum entropy model is a species distribution model based on the maximum entropy theory. After more than ten years of development, the calculation method of the maximum entropy model is iterative and tends to be stable, and has been applied systematically and maturely in the prediction of terrestrial biological suitable areas. In the marine environment, the application of maximum entropy model has also entered a stage of rapid development. Due to the lack of data, the application of maximum entropy model still needs continuous exploration. The maximum entropy model has the advantage of dealing with small samples. Application results provide key data have critically supported issues such as the protection of species, biological communities and biodiversity, the control and early warning of biological invasion events and the reduction of consumption and improving efficiency of aquaculture. At the same time, it has great development prospects in marine paleoecology research, marine genetic resources acquisition and marine extreme environmental biodiversity protection.