Abstract: In order to understand the heavy metal pollution situation and feeding risk of marine commercial orga nisms in Xiamen Bay， 13 marine commercial organisms were captured in Xiamen Bay for four seasons from August 2019 to April 2020. The contentrations of 7 heavy metals (Cr, Ni, Cu, Zn, As, Cd and Pb) in their muscle tissues were analyzed by ICP-MS, different evaluation models were used to evaluate the health risks of human and Indo-Pacific humpback dolphin. The results showed that， firstly, concentrations of Zn, As and Cu in fishes and cephalopods were higher， while the concentrations of Pb and Cd were lower， comparatively. Secondly, the residues of most heavy metals in fishes are significantly higher in summer than in other seasons， which may be caused by rich preys and active metabolism in summer. Thirdly, the evaluation results of single factor pollution index (SFI) method and target hazard quotient (THQ) evaluation method showed that the residue of As in samples not only exceeded the national standard of food safety limitation， but also caused potential risks to human health. The pollution of As in Xiamen Bay should be given a particular attention although no analysis of different forms of As in this study. The follow-up research should focus on the main existing forms of As in organisms in Xiamen Bay. It is also necessary to improve the accuracy of health risk assessment， the data support for the supervision of local regulatory authorities and the formulation of relevant policies. As the feeding behaviors of Indo-Pacific humpback dolphin is different from human being, the evaluation results can only be taken as reference.